COVID-19 Vaccination During Pregnancy

A global health crisis named coronavirus disease-2019 (COVID-19) pandemic was caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). COVID-19 pandemic created an immediate occasion to establish strategies for vaccination. Increasing evidence suggests the pregnancy-related COVID-19 risks substantially above the risk of non-pregnant woman. Women with pregnancy and lactation were not included in COVID-19 vaccination studies. To date, subsequent data from pregnant COVID-19 vaccinated women showed safety and efficacy during pregnancy. There is no evidence of harmful effects on pregnancy, fetal development, parturition and postnatal development both directly and indirectly for the COVID-19 vaccines. Vaccination for pregnant women is a healthy and safe way to prevent infection of SARS-CoV-2 and should be considered. From the knowledge of similar prior non-COVID-19 vaccine trials’ experience, reproductive and developmental toxicology trials from animals, datas from trials of humans and different advisory committees of healthcare have published guidelines supporting vaccination for COVID-19 during pregnancy and breastfeeding.