E-ISSN: 2791-8823
Cam & Sakura Medical Journal
Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings [Cam Sakura Med J]
Cam Sakura Med J. 2022; 2(2): 70-74 | DOI: 10.4274/csmedj.galenos.2022.2021-12-5

Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings

Handan Eren1, Tuce Soylemez Akkurt1, Hazal Izol Ozmen1, Mehmet Ali Nazli2, Ebru Sen3, Soykan Arikan3, Burcin Pehlivanoglu4
1University of Health Sciences Turkey, Baakehir am and Sakura City Hospital, Department of Pathology, stanbul, Turkey
2University of Health Sciences Turkey, Baakehir am and Sakura City Hospital, Department of Radiology, stanbul, Turkey
3University of Health Sciences Turkey, Baakehir am and Sakura City Hospital, Department of General Surgery, stanbul, Turkey
4Dokuz Eylul University Hospital, Department of Pathology, Izmir, Turkey

Objective: Image-guided breast biopsy is commonly used for diagnosis of breast lesions. Breast ultrasound (US), which is also used for screening purposes, is an important tool to guide biopsies. In this study, we evaluated the radiologic-histopathologic correlation in patients who underwent US-guided breast biopsy.
Material and Methods: A total of 126 biopsies from 116 consecutive cases were included. Patients US and histopathological findings were retrospectively reviewed.
Results: All patients were female. Median age was 4412 (range; 16-66 years old). Two patients (2%) had bilateral, 8 (7%) had multifocal lesions. Breast Imaging Reporting and Data System (BI-RADS) was used for 115 lesions (91%). Three cases (2%) were BI-RADS 2, 27% (n=34) BI-RADS 3, 35% (n=44) BI-RADS 4, 25% (n=32) BI-RADS 5 and 2% (n=2) BI-RADS 6. Eight biopsies composed of normal breast tissue, which had been scored as BI-RADS 3 or 4, were considered inadequate. More than one-third (37%; n=47) were malignant as 28% (n=35) were consistent with fibroepithelial lesions and 11% (n=14) with inflammatory lesions. Major radiologic-histopathologic discordance was observed in only 2 cases, while there was minor discordance in 14. Ten of the 14 cases (11%) with minor discordance were BI-RADS 4 lesions and minor discordance was more common for benign lesions (p=0.013).
Conclusion: Our findings demonstrate a high radiologic-histopathologic correlation rate in US-guided breast biopsy samples. We observed the highest discordance in BI-RADS 4 lesions, suggesting that histopathological verification is necessary in patients with BI-RADS 4 lesions to exclude malignancy.

Keywords: Biopsy, breast, histopathology, radiology, ultrasonography

Handan Eren, Tuce Soylemez Akkurt, Hazal Izol Ozmen, Mehmet Ali Nazli, Ebru Sen, Soykan Arikan, Burcin Pehlivanoglu. Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings. Cam Sakura Med J. 2022; 2(2): 70-74

Corresponding Author: Burcin Pehlivanoglu, Trkiye
Manuscript Language: English
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