Update on COVID-19 in Children

Since the start of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, it has been clear that most children who have been infected with the virus remain asymptomatic or very mildly ill. Since asymptomatic children are less often examined, the true prevalence of asymptomatic SARS-CoV-2 infection is probably underestimated. Children rarely get anosmia/ageusia, yet it is the best indicator of a positive SARS-CoV-2 test. Children with coronavirus disease-2019 (COVID-19) generally have a lower risk of hospitalization and potentially fatal consequences. Immunization with effective and safe vaccine in children and adolescents is likely to provide protection against severe COVID-19 infection. Recent results from COVID-19 vaccine studies indicate good efficacy and tolerability in children.