Cam Sakura Med J. 2023; 3(3): 116-119 | DOI: 10.4274/csmedj.galenos.2023.2023-5-2
Active Pulmonary Tuberculosis During Interferon Beta-1a Therapy in a Child with Multiple Sclerosis: A Case Report
Pakize Cennetoğlu1, Zeynep Öz1, Canan Caymaz2, Peren Perk Yücel1, Pınar Arıcan1, İhsan Kafadar11University of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Clinic of Pediatrics, Division of Pediatric Neurology, İstanbul, Turkey
2University of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Clinic of Pediactrics, Division of Pediatric Infectious Diseases, İstanbul, Turkey
Interferon (IFN) beta (β) is a potent anti-inflammatory and immunomodulatory agent that is used for treating patients with multiple sclerosis (MS). In this study, we present the case of a 15-year-old female patient diagnosed with MS and treated with IFN β-1a for six months who was referred to the emergency department with complaints of fatigue, fever, and coughing. She was diagnosed with pulmonary tuberculosis (TB). IFN β-1a therapy was stopped and anti-TB treatment was initiated. After nine months of therapy, she recovered from TB. This case presented with a rare side effect during the treatment of pediatric-onset MS with immunomodulatory drugs, demonstrating the importance of screening and close follow-up of patients with TB.
Keywords: Case report, interferon beta, multiple sclerosis, pediatric neurology, tuberculosis
Pakize Cennetoğlu, Zeynep Öz, Canan Caymaz, Peren Perk Yücel, Pınar Arıcan, İhsan Kafadar. Active Pulmonary Tuberculosis During Interferon Beta-1a Therapy in a Child with Multiple Sclerosis: A Case Report. Cam Sakura Med J. 2023; 3(3): 116-119
Corresponding Author: Pakize Cennetoğlu, Türkiye
Manuscript Language: English